REGULATORY

Reblozyl to Face 8% Cut, Vyloy 4% in February: CEA Adjustment

November 6, 2025
Japan will apply a price reduction of roughly 8.3% for Bristol Myers Squibb’s Reblozyl (luspatercept) and 4.3% for Astellas Pharma’s Vyloy (zolbetuximab) under the cost-effectiveness assessment (CEA) scheme, effective February 1 next year. Reblozyl’s current NHI prices — 184,552 yen…

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